Seasonal trends of blood pressure during pregnancy in Japan: the Babies and their Parents' Longitudinal Observation in Suzuki Memorial Hospital in Intrauterine Period study

被引：59

作者：

Metoki, Hirohito ^{[1
,2
,8
]}

Ohkubo, Takayoshi ^{[3
,5
]}

Watanabe, Yumiko ^{[1
,6
]}

Nishimura, Misato ^{[1
]}

Sato, Yurie ^{[1
]}

Kawaguchi, Maiko ^{[3
]}

Hara, Azusa ^{[1
,5
,8
]}

Hirose, Takuo ^{[1
,5
,8
]}

Obara, Taku ^{[1
,5
,8
]}

Asayama, Kei ^{[5
]}

Kikuya, Masahiro ^{[1
]}

Yagihashi, Katsuyo ^{[7
]}

Matsubara, Yoichi ^{[2
]}

Okamura, Kunihiro ^{[4
]}

Mori, Shigeru ^{[7
]}

Suzuki, Masakuni ^{[7
]}

Imai, Yutaka ^{[1
,5
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci & Med, Dept Clin Pharmacol & Therapeut, Sendai, Miyagi 980, Japan

[2] Tohoku Univ, Grad Sch Pharmaceut Sci & Med, Dept Med Genet, Sendai, Miyagi 980, Japan

[3] Tohoku Univ, Grad Sch Pharmaceut Sci & Med, Dept Planning Drug Dev & Clin Evaluat, Sendai, Miyagi 980, Japan

[4] Tohoku Univ, Grad Sch Pharmaceut Sci & Med, Dept Obstet & Gynecol, Sendai, Miyagi 980, Japan

[5] Tohoku Univ, 21st Century COE Program, Comprehens Res & Educ Ctr Planning Drug Dev & Cli, Sendai, Miyagi 980, Japan

[6] Tohoku Univ, Inst Int Adv Res & Educ, Sendai, Miyagi 980, Japan

[7] Suzuki Mem Hosp, Iwanuma, Japan

[8] Japan Soc Promot Sci, Tokyo, Japan

来源：

JOURNAL OF HYPERTENSION | 2008年 / 26卷 / 12期

基金：

日本学术振兴会;

关键词：

blood pressure measurement/monitoring; clinical science; home blood pressure; preeclampsia/pregnancy;

D O I：

10.1097/HJH.0b013e32831364a7

中图分类号：

R6 [外科学];

学科分类号：

1002 [临床医学]; 100210 [外科学];

摘要：

Objective Blood pressure (BP) increases both in winter and in the last trimester of pregnancy. Some interaction seems to exist between season and gestational age. The present study observed home BP values during pregnancy with adjustment for seasonal variation and gestational age. Methods We observed 10 353 home BP measurements from 101 normal pregnant women attending a maternity hospital in Japan. Home BP values were examined by mixed linear model adjusting for meteorological data and gestational age. Results The lowest home BP values were observed in the second trimester [mean (+/- standard deviation) systolic/diastolic BP, 101.8 +/- 7.9/59.8 +/- 5.8mmHg at gestational week 20]. In the last trimester, home BP values gradually increased and the values after gestational week 26 were significantly higher than those at gestational week 20 (110.1 +/- 9.7/66.8 +/- 7.7 mmHg at gestational week 40). A 10 degrees C increase in daily minimum outdoor temperature was associated with a mean reduction of 2.5/2.5mmHg (D systolic BP/Delta diastolic BP: 95% confidence interval, 2.3/2.4 to 2.6/2.7mmHg) in home BP with adjustment for gestational age. The largest and smallest estimated home BP changes during pregnancy were 12.8/12.5 and 3.1/3.0 mmHg in pregnant woman who delivered in January and July, respectively. Conclusion Interactions among BP, season and gestational age should be considered when evaluating BP in pregnant women. Risks associated with high BP might be underestimated in pregnant woman in summer who will deliver in winter. J Hypertens 26: 2406-2413 (C) 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins.

引用

页码：2406 / 2413

页数：8

共 18 条

[1]

Seasonal variation in gestational blood pressure [J].