In situformation of injectable hydrogels for chronic wound healing

被引:191
作者
Gao, Yunfen [1 ]
Li, Zhen [1 ]
Huang, Jun [1 ,2 ]
Zhao, Meng [3 ]
Wu, Jun [1 ,2 ]
机构
[1] Sun Yat Sen Univ, Sch Biomed Engn, Shenzhen 518107, Peoples R China
[2] Sun Yat Sen Univ, Affiliated Hosp 7, Shenzhen 518107, Peoples R China
[3] Shenzhen Lansi Inst Artificial Intelligence Med, Shenzhen, Guangdong, Peoples R China
基金
中国国家自然科学基金; 中国博士后科学基金;
关键词
DRUG-DELIVERY; COMPOSITE HYDROGEL; PHASE-TRANSITION; PEPTIDE HYDROGEL; STEM-CELLS; CHITOSAN; RELEASE; DRESSINGS; THERMOGEL; POLYMERS;
D O I
10.1039/d0tb01074j
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
082905 [生物质能源与材料]; 100103 [病原生物学];
摘要
Hydrogels have been widely used in wound healing treatment over the past decade. Injectable hydrogels have become a major research focus due to their unique advantages. Compared to traditional hydrogels, injectable hydrogels have good fluidity. When injected into the wound as a solution, they form a gelin situthat can fill the wound in three dimensions. This enables them to reach deep and irregular wounds that traditional hydrogels cannot fill. Injectable hydrogels greatly reduce the need for invasive surgery and are well-suited for chronic wound repair. This review article categorizes hydrogels that are commonly used in chronic wound repair according to their sources and reviews the current applications of the different types of injectable hydrogels in chronic wound repair.
引用
收藏
页码:8768 / 8780
页数:13
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