Transition-Metal-Free Trifluoromethylaminoxylation of Alkenes

被引：309

作者：

Li, Yi ^{[1
]}

Studer, Armido ^{[1
]}

机构：

[1] Univ Munster, Inst Organ Chem, D-48149 Munster, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 33期

关键词：

radicals; single-electron transfer; synthetic methods; TEMPO; trifluoromethylation; COPPER-CATALYZED TRIFLUOROMETHYLATION; POLAR CROSSOVER REACTIONS; SILYL ENOL ETHERS; RADICAL TRIFLUOROMETHYLATION; AROMATIC-COMPOUNDS; MEDIATED TRIFLUOROMETHYLATION; PERFLUOROALKYL IODIDES; RUTHENIUM(II) COMPLEX; PHOTOREDOX CATALYSIS; CHEMISTRY;

D O I：

10.1002/anie.201202623

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

No transition metal! Fluorinated hypervalent-iodine reagents react with TEMPONa in the presence of an alkene under mild conditions to give the corresponding perfluoroalkylaminoxylation products. These radical addition/trapping reactions occur with high stereoselectivity using commercially available reagents, and the product alkoxyamines are readily transformed into the corresponding alcohols. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：8221 / 8224

页数：4

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