Outbreak of Escherichia coli O157:H7 infection in a large family

被引：12

作者：

Ludwig, K

Ruder, H

Bitzan, M

Zimmermann, S

Karch, H

机构：

[1] UNIV HAMBURG, KINDERKLIN, D-20246 HAMBURG, GERMANY

[2] HOSP SICK CHILDREN, TORONTO, ON M5G 1X8, CANADA

[3] UNIV WURZBURG, INST HYG & MIKROBIOL, WURZBURG, GERMANY

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 1997年 / 16卷 / 03期

关键词：

D O I：

10.1007/BF01709588

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

An outbreak of bloody and nonbloody diarrhoea caused by Escherichia coli O157:H7 including one case of haemolytic uraemic syndrome (HUS) and two cases of haemolytic anaemia, in five siblings (aged 2.5 to 11.3 years) and their playmate was investigated. Using sorbitol-MacConkey agar, colony blot hybridisation, and immunomagnetic separation, Shiga toxin 2-producing Escherichia coli O157:H7 was isolated from all children but the HUS patient; however, this patient had high immunoglobulin M antibody titres against Escherichia coli O157 lipopolysaccharide. Escherichia coli O157 isolates from all patients were indistinguishable in serotype, virulence properties, and genomic background, indicating that the same strain caused the infections. These data confirm the importance of person-to-person transmission.

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收藏

页码：238 / 241

页数：4

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