Stereochemical resolution of racemates, in HPLC, using a chiral stationary phase based upon immobilized α-chymotrypsin.: II.: Enzyme chiral separations

被引：12

作者：

Félix, G ^{[1
]}

Descorps, V ^{[1
]}

机构：

[1] ENSCPB, F-33402 Talence, France

来源：

CHROMATOGRAPHIA | 1999年 / 49卷 / 11-12期

关键词：

column liquid chromatography; alpha-chymotrypsin-CSP; enzymatic chiral separations; loadability evaluation;

D O I：

10.1007/BF02466901

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Several racemates has been resolved according to an enzymatic recognition mechanism on an alpha-chymotrypsin chiral stationary phase. The loadability of the ACHT-CSP has been evaluated both in buffered and non-buffered mobile phases under the enzymatic process and compared with the loading capacity obtained by the structural recognition process.

引用

收藏

页码：606 / 614

页数：9

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