Studies on neurosteroids .6. Characterization of fatty acid esters of pregnenolone and dehydroepiandrosterone in rat brains using liquid chromatography mass spectrometry

被引：10

作者：

Shimada, K

Mukai, Y

Nakajima, A

Naka, Y

机构：

[1] Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 920

来源：

ANALYTICAL COMMUNICATIONS | 1997年 / 34卷 / 05期

关键词：

D O I：

10.1039/a701036b

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The separation and characterization of 3-fatty acid esters (stearate, palmitate) of pregnenolone and dehydroepiandrosterone in rat brains were carried out using liquid chromatography atmospheric pressure chemical ionization mass spectrometry (LC-APCI-MS) operating in the positive-ion mode. The fatty acid esters obtained from rat brains were derivatized with O-methylhydroxylamine to give the respective methyloximes, which were identified by comparison with authentic samples during the course of LC-APCI-MS.

引用

页码：145 / 146

页数：2

共 3 条

[1] STEROIDS AND THEIR CONJUGATES IN THE MAMMALIAN BRAIN [J].