Stepwise syntheses of core-modified, meso-substituted porphyrins

被引：82

作者：

Heo, PY ^{[1
]}

Shin, K ^{[1
]}

Lee, CH ^{[1
]}

机构：

[1] KANGWEON NATL UNIV,DEPT CHEM,CHUNCHON 200701,SOUTH KOREA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 02期

关键词：

D O I：

10.1016/0040-4039(95)02127-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Simple conditions are discovered to afford modified tripyrrin derivatives by condensation of 2,5-bis(alpha-hydroxymethyl)pyrrole, thiophene and furan derivatives with pyrrole in the presence of acid catalyst. The core-modified porphyrins were synthesized by acid catalyzed 3 + 1 condensation of modified tripyrrins with 2,5-bis(alpha-hydroxymethyl)-substituted pyrrole, thiophene or furan. This new process gives a single porphyrin isomer and overcome the synthetic problems associated with separation and purification of regioisomeric mixtures.

引用

页码：197 / 200

页数：4

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