Upper respiratory infections in children: Response to endonasal administration of IGA

被引：17

作者：

Giraudi, V ^{[1
]}

Riganti, C ^{[1
]}

Torales, MR ^{[1
]}

Sedola, H ^{[1
]}

Gaddi, E ^{[1
]}

机构：

[1] PEDRO ELIZALDE CHILDRENS HOSP,DIV IMMUNOL,RA-1270 BUENOS AIRES,DF,ARGENTINA

来源：

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY | 1997年 / 39卷 / 02期

关键词：

upper respiratory infections; children; IgA enriched preparation; endonasal administration;

D O I：

10.1016/S0165-5876(96)01472-3

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Children, 36, predisposed to frequent upper respiratory infections were treated with endonasal administration of an IgA enriched preparation or placebo in a randomized double blind trial. We found a reduction in the number of infectious episodes and in the number of enlarged regional lymph nodes. Also, an increase of IgA levels in saliva in the treated group was observed, probably not only due to the effect of IgA supplementation, but also to an immunoregulatory effect on the mucosa caused by the preparation administered. We found this therapy very useful in the prophylaxis of upper respiratory infections, being the nasal administration very convenient to be used in children. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：103 / 110

页数：8

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