Assessment of autonomic nervous system function in patients with Behcet's disease by spectral analysis of heart rate variability

被引:26
作者
Aksöyek, S
Aytemir, K
Özer, N
Özcebe, O
Oto, A
机构
[1] Hacettepe Univ, Fac Med, Dept Cardiol, TR-06100 Ankara, Turkey
[2] Hacettepe Univ, Fac Med, Dept Hematol, TR-06100 Ankara, Turkey
来源
JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM | 1999年 / 77卷 / 2-3期
关键词
Behcet's disease; autonomic nervous system; heart rate variability;
D O I
10.1016/S0165-1838(99)00045-4
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
The purpose of this study was to evaluate the autonomic nervous system (ANS) function in patients with Behcet's disease by using power spectral analysis of heart rate variability (HRV). The study population consisted of 71 patients with Behcet's disease, and 26 normal volunteers. HRV was measured by power spectral analysis in supine and standing position. In supine position, Behcet's patients had increased low frequency component in absolute (LF) and normalized units (LF nU) but had lower values of high frequency component in absolute (HF) and normalized units (HF nU) than the controls (P < 0.05). In standing position, higher values were obtained in LF and LF nU but lower values of HF and HF nU in Behcet's patients than controls (P < 0.05). LF/HF was significantly higher in patients bath in supine (2.5 +/- 1.0 vs. 1.2 +/- 0.8, P = 0.001) and standing (21.9 +/- 7 vs. 1.8 +/- 0.3, P < 0.001) positions. Our data suggest that patients with Behcet's disease may have asymptomatic ANS dysfunction, which is in the form of increased sympathetic and decreased parasympathetic modulation, and power spectral analysis of HRV is beneficial in assessing the ANS function. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:190 / 194
页数:5
相关论文
共 30 条
[1]
POWER SPECTRUM ANALYSIS OF HEART-RATE FLUCTUATION - A QUANTITATIVE PROBE OF BEAT-TO-BEAT CARDIOVASCULAR CONTROL [J].
AKSELROD, S ;
GORDON, D ;
UBEL, FA ;
SHANNON, DC ;
BARGER, AC ;
COHEN, RJ .
SCIENCE, 1981, 213 (4504) :220-222
[2]
BEAT TO BEAT VARIABILITY IN CARDIOVASCULAR VARIABLES - NOISE OR MUSIC [J].
APPEL, ML ;
BERGER, RD ;
SAUL, JP ;
SMITH, JM ;
COHEN, RJ .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1989, 14 (05) :1139-1148
[3]
QT dispersion and autonomic nervous system function in patients with type 1 diabetes [J].
Aytemir, K ;
Aksöyek, S ;
Özer, N ;
Gürlek, A ;
Oto, A .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 1998, 65 (01) :45-50
[4]
Increased QT dispersion in the absence of QT prolongation in patients with Behcet's disease and ventricular arrhythmias [J].
Aytemir, K ;
Ozer, N ;
Aksoyek, S ;
Ozcebe, O ;
Kabakci, G ;
Oto, A .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 1998, 67 (02) :171-175
[5]
Behçet H, 1937, DERMATOL WOCHENSCHR, V105, P1152
[6]
CARDIAC INVOLVEMENT IN BEHCETS-DISEASE [J].
BOWLES, CA ;
NELSON, AM ;
HAMMILL, SC ;
ODUFFY, JD .
ARTHRITIS AND RHEUMATISM, 1985, 28 (03) :345-348
[7]
Camm AJ, 1996, CIRCULATION, V93, P1043
[8]
BEHCETS-DISEASE - CARDIAC AND PULMONARY INVOLVEMENT [J].
CANDAN, I ;
EROL, C ;
SONEL, A ;
AKALIN, H .
EUROPEAN HEART JOURNAL, 1986, 7 (11) :999-1002
[9]
NEURO-BEHCETS DISEASE - FACTORS HAMPERING PROPER DIAGNOSIS [J].
DEVLIN, T ;
GRAY, L ;
ALLEN, NB ;
FRIEDMAN, AH ;
TIEN, R ;
MORGENLANDER, JC .
NEUROLOGY, 1995, 45 (09) :1754-1757
[10]
DILSEN G, 1991, INFL DIS TH, V8, P127