Plasma total homocysteine and subarachnoid haemorrhage in a co-factor replete population

被引：8

作者：

McEvoy, AW

Marras, C

Kitchen, ND

Briddon, A

机构：

[1] UCL Natl Hosp Neurol & Neurosurg, Dept Surg Neurol, London WC1N 3BG, England

[2] UCL Natl Hosp Neurol & Neurosurg, Dept Clin Biochem, London WC1N 3BG, England

[3] Univ Milan, Maggiore Policlin Hosp, Inst Neurosurg, IRCCS, Milan, Italy

来源：

AMINO ACIDS | 2001年 / 21卷 / 03期

关键词：

amino acids; homocysteine; subarachnoid haemorrhage; stroke; folate; vitamin B12;

D O I：

10.1007/s007260170009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mild hyperhomocysteinaemia is a postulated risk factor for occlusive vascular disease, including stroke. Subarachnoid haemorrhage (SAH) has an annual incidence of 10-20 per 100,000 and accounts for 5-10% of all strokes. Measurement of plasma total homocysteine (tHcy) in a cohort of vitamin B12 and folate replete patients did not reveal any association between tHcy and the aetiology of SAH.

引用

页码：237 / 241

页数：5

共 12 条

[1] A PROSPECTIVE-STUDY OF ACUTE CEREBROVASCULAR-DISEASE IN THE COMMUNITY - THE OXFORDSHIRE COMMUNITY STROKE PROJECT 1981-86 .2. INCIDENCE, CASE FATALITY RATES AND OVERALL OUTCOME AT ONE YEAR OF CEREBRAL INFARCTION, PRIMARY INTRACEREBRAL AND SUBARACHNOID HEMORRHAGE
BAMFORD, J
SANDERCOCK, P
DENNIS, M
BURN, J
WARLOW, C
[J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1990, 53 (01) : 16 - 22
[2] BRATTSTROM L, 1992, NEUROL RES, V14, P81, DOI 10.1080/01616412.1992.11740017
[3] Total plasma homocysteine as part of the routine aminogram by ion-exchange chromatography
Briddon, A
[J]. AMINO ACIDS, 1998, 15 (03) : 235 - 239
[4] Vegan diet-based lifestyle program rapidly lowers homocysteine levels
DeRose, DJ
Charles-Marcel, ZL
Jamison, JM
Muscat, JE
Braman, MA
McLane, GD
Mullen, JK
[J]. PREVENTIVE MEDICINE, 2000, 30 (03) : 225 - 233
[5] Donnelly JG, 2000, ANN CLIN BIOCHEM, V37, P304
[6] TOTAL PLASMA HOMOCYSTEINE - INFLUENCE OF SOME COMMON PHYSIOLOGICAL VARIABLES
FERMO, I
DEVECCHI, E
DANGELO, SV
DANGELO, A
PARONI, R
[J]. AMINO ACIDS, 1993, 5 (01) : 17 - 21
[7] Plasma homocysteine as a risk factor for vascular disease - The European concerted action project
Graham, IM
Daly, LE
Refsum, HM
Robinson, K
Brattstrom, LE
Ueland, PM
PalmaReis, RJ
Boers, GHJ
Sheahan, RG
Israelsson, B
Uiterwaal, CS
Meleady, R
McMaster, D
Verhoef, P
Witteman, J
Rubba, P
Bellet, H
Wautrecht, JC
deValk, HW
Luis, ACS
ParrotRoulaud, FM
Tan, KS
Higgins, I
Garcon, D
Medrano, MJ
Candito, M
Evans, AE
Andria, G
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 277 (22): : 1775 - 1781
[8] Homocysteine and hemostasis: Pathogenetic mechanisms predisposing to thrombosis
Harpel, PC
Zhang, XX
Borth, W
[J]. JOURNAL OF NUTRITION, 1996, 126 (04) : S1285 - S1289
[9] Incidence of subarachnoid hemorrhage - Role of region, year, and rate of computed tomography: A meta-analysis
Linn, FHH
Rinkel, GJE
Algra, A
vanGijn, J
[J]. STROKE, 1996, 27 (04) : 625 - 629
[10] HOMOCYSTEINE THEORY OF ARTERIOSCLEROSIS
MCCULLY, KS
WILSON, RB
[J]. ATHEROSCLEROSIS, 1975, 22 (02) : 215 - 227

← 1 2 →