The evolution of the diagnosis and management of women with an early pregnancy loss has been a success story. The mortality from ectopic pregnancy has objectively been decreased in the past few decades. However, modern management has resulted in a new set of issues. Over-interpretation of a single ultrasound, misunderstanding of the utility of serial hCG values, and inappropriate use of methotrexate can result in iatrogenic complications. Modern management has successfully improved the diagnosis of ectopic pregnancy before rupture; it should now also focus on ensuring that an intrauterine pregnancy is not interrupted as a result of diagnosis and treatment. This article reviews some of the pitfalls of the modern management of early pregnancy failure and introduces a series of articles on the subject. (Fertil Steril (R) 2012;98:1061-5. (C)2012 by American Society for Reproductive Medicine.)
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页码:1061 / 1065
页数:5
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[1]
Addar Mohammed Hassan, 2004, J Obstet Gynaecol Can, V26, P1001
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Univ Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Univ Penn, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USAUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Barnhart, Kurt
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van Mello, Norah M.
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Univ Amsterdam, Acad Med Ctr, Dept Obstet & Gynaecol, NL-1105 AZ Amsterdam, NetherlandsUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
van Mello, Norah M.
;
Bourne, Tom
论文数: 0引用数: 0
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Univ London, Early Pregnancy Gynaecol Ultrasound & MAS Unit, London, England
Katholieke Univ Leuven, Univ Hosp Gasthuisberg, Dept Obstet & Gynaecol, Leuven, BelgiumUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Bourne, Tom
;
Kirk, Emma
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Univ London, Early Pregnancy Gynaecol Ultrasound & MAS Unit, London, EnglandUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Kirk, Emma
;
Van Calster, Ben
论文数: 0引用数: 0
h-index: 0
机构:
Katholieke Univ Leuven, Dept Elect Engn ESAT SISTA, Leuven, BelgiumUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Van Calster, Ben
;
Bottomley, Cecilia
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Univ London, Early Pregnancy Gynaecol Ultrasound & MAS Unit, London, EnglandUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Bottomley, Cecilia
;
Chung, Karine
论文数: 0引用数: 0
h-index: 0
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Univ So Calif, Div Reprod Endocrinol & Infertil, Los Angeles, CA USAUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Chung, Karine
;
Condous, George
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Univ Sydney, Nepean Hosp, Early Pregnancy & Adv Endosurg Unit, Sydney, NSW 2006, AustraliaUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Condous, George
;
Goldstein, Steven
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NYU, Dept Obstet & Gynecol, Sch Med, New York, NY 10016 USAUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Goldstein, Steven
;
Hajenius, Petra J.
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Univ Amsterdam, Acad Med Ctr, Dept Obstet & Gynaecol, NL-1105 AZ Amsterdam, NetherlandsUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Hajenius, Petra J.
;
Mol, Ben Willem
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机构:
Univ Amsterdam, Acad Med Ctr, Dept Obstet & Gynaecol, NL-1105 AZ Amsterdam, Netherlands
Univ Amsterdam, Acad Med Ctr, Dept Clin Epidemiol & Biostat & Bioinformat, NL-1105 AZ Amsterdam, NetherlandsUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Mol, Ben Willem
;
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Molinaro, Thomas
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O'Brien, Katherine L. O'Flynn
论文数: 0引用数: 0
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机构:Univ Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
O'Brien, Katherine L. O'Flynn
;
Husicka, Richard
论文数: 0引用数: 0
h-index: 0
机构:
Masaryk Univ, Dept Gynecol, Brno, Czech Republic
Univ Hosp, Brno, Czech RepublicUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Husicka, Richard
;
Sammel, Mary
论文数: 0引用数: 0
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机构:
Univ Penn, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USAUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Sammel, Mary
;
Timmerman, Dirk
论文数: 0引用数: 0
h-index: 0
机构:
Katholieke Univ Leuven, Univ Hosp Gasthuisberg, Dept Obstet & Gynaecol, Leuven, BelgiumUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
机构:
Univ Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Univ Penn, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USAUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Barnhart, Kurt
;
van Mello, Norah M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Amsterdam, Acad Med Ctr, Dept Obstet & Gynaecol, NL-1105 AZ Amsterdam, NetherlandsUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
van Mello, Norah M.
;
Bourne, Tom
论文数: 0引用数: 0
h-index: 0
机构:
Univ London, Early Pregnancy Gynaecol Ultrasound & MAS Unit, London, England
Katholieke Univ Leuven, Univ Hosp Gasthuisberg, Dept Obstet & Gynaecol, Leuven, BelgiumUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Bourne, Tom
;
Kirk, Emma
论文数: 0引用数: 0
h-index: 0
机构:
Univ London, Early Pregnancy Gynaecol Ultrasound & MAS Unit, London, EnglandUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Kirk, Emma
;
Van Calster, Ben
论文数: 0引用数: 0
h-index: 0
机构:
Katholieke Univ Leuven, Dept Elect Engn ESAT SISTA, Leuven, BelgiumUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Van Calster, Ben
;
Bottomley, Cecilia
论文数: 0引用数: 0
h-index: 0
机构:
Univ London, Early Pregnancy Gynaecol Ultrasound & MAS Unit, London, EnglandUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Bottomley, Cecilia
;
Chung, Karine
论文数: 0引用数: 0
h-index: 0
机构:
Univ So Calif, Div Reprod Endocrinol & Infertil, Los Angeles, CA USAUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Chung, Karine
;
Condous, George
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sydney, Nepean Hosp, Early Pregnancy & Adv Endosurg Unit, Sydney, NSW 2006, AustraliaUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Condous, George
;
Goldstein, Steven
论文数: 0引用数: 0
h-index: 0
机构:
NYU, Dept Obstet & Gynecol, Sch Med, New York, NY 10016 USAUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Goldstein, Steven
;
Hajenius, Petra J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Amsterdam, Acad Med Ctr, Dept Obstet & Gynaecol, NL-1105 AZ Amsterdam, NetherlandsUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Hajenius, Petra J.
;
Mol, Ben Willem
论文数: 0引用数: 0
h-index: 0
机构:
Univ Amsterdam, Acad Med Ctr, Dept Obstet & Gynaecol, NL-1105 AZ Amsterdam, Netherlands
Univ Amsterdam, Acad Med Ctr, Dept Clin Epidemiol & Biostat & Bioinformat, NL-1105 AZ Amsterdam, NetherlandsUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Mol, Ben Willem
;
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Molinaro, Thomas
;
O'Brien, Katherine L. O'Flynn
论文数: 0引用数: 0
h-index: 0
机构:Univ Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
O'Brien, Katherine L. O'Flynn
;
Husicka, Richard
论文数: 0引用数: 0
h-index: 0
机构:
Masaryk Univ, Dept Gynecol, Brno, Czech Republic
Univ Hosp, Brno, Czech RepublicUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Husicka, Richard
;
Sammel, Mary
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USAUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
Sammel, Mary
;
Timmerman, Dirk
论文数: 0引用数: 0
h-index: 0
机构:
Katholieke Univ Leuven, Univ Hosp Gasthuisberg, Dept Obstet & Gynaecol, Leuven, BelgiumUniv Penn, Med Ctr, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA