Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in Parkinson's disease patients: A double-blind single-dose study

被引：39

作者：

Merello, M ^{[1
]}

Pikielny, R ^{[1
]}

Cammarota, A ^{[1
]}

Leiguarda, R ^{[1
]}

机构：

[1] RAUL CARREA INST NEUROL RES,FLENI,DEPT NEUROL,RA-1428 BUENOS AIRES,DF,ARGENTINA

来源：

CLINICAL NEUROPHARMACOLOGY | 1997年 / 20卷 / 02期

关键词：

apomorphine; Dispersible Madopar; motor fluctuations; ''on-off'' periods; Parkinson's disease;

D O I：

10.1097/00002826-199704000-00008

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Twelve parkinsonian patients with severely fluctuating symptoms were given a single dose of apomorphine or Dispersible Madopar on 2 consecutive days, to confirm the latter drug's usefulness in ''off'' period rescue. According to our results, apomorphine proved faster in reverting ''off'' periods and should still be regarded as the drug of choice for this treatment modality.

引用

页码：165 / 167

页数：3

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