Biotransformation of the germacrane type sesquiterpene curdione by suspension cultured cells of Lonicera japonica

被引：22

作者：

Horiike, T ^{[1
]}

Ohshiro, M ^{[1
]}

Kuroyanagi, M ^{[1
]}

机构：

[1] UNIV SHIZUOKA,SCH PHARMACEUT SCI,SHIZUOKA 422,JAPAN

来源：

PHYTOCHEMISTRY | 1997年 / 44卷 / 04期

关键词：

Lonicera japonica; biotransformation; suspension cultured cells; curdione; sesquiterpene; 2-hydroxycurdione; 1,10-epoxycurdione;

D O I：

10.1016/S0031-9422(96)00569-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Curdione, a sesquiterpene with a germacrane skeleton, was incubated with suspension cultured cells induced from calli of Lonicera japonica for 10 days. The ethyl acetate-soluble fraction of the culture medium gave a number of products, of which six were shown to be (2S)-2-hydroxycurdione, (2R)-2-hydroxycurdione, (8S)-6-hydroxycurdione, (2R, 8S)-8-hydro-2-hydroxycurdione, (1S, 10S)-1,10-epoxycurdione and (1R, 10R)-1.10-epoxycurdione, respectively. Copyright (C) 1997 Elsevier Science Ltd.

引用

页码：627 / 632

页数：6

共 13 条

[1] BIOTRANSFORMATION OF GERMACRANE-TYPE SESQUITERPENOIDS BY ASPERGILLUS-NIGER [J].