Dengue epidemic in the State of Rio Grande do Norte, Brazil, in 1997

被引：27

作者：

Cunha, RV

Schatzmayr, HG

Miagostovich, MP

Barbosa, AMA

Paiva, FG

Miranda, RMO

Ramos, CCF

Coelho, JCO

dos Santos, FB

Nogueira, RMR

机构：

[1] Univ Fed Mato Grosso Sul, Disciplina Doencas Infecciosas & Parasitarias, Campo Grande, MS, Brazil

[2] Inst Oswaldo Cruz FIOCRUZ, Rio De Janeiro, Brazil

[3] Inst Oswaldo Cruz FIOCRUZ, Dept Virol, Lab Flavivirus, Rio De Janeiro, Brazil

[4] IOC FIOCRUZ, Hosp Evandro Chagas, Manguinho, Brazil

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1999年 / 93卷 / 03期

关键词：

dengue; DEN-1; DEN-2; dengue haemorrhagic fever; risk factors; Brazil;

D O I：

10.1016/S0035-9203(99)90008-1

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

During 1997 a large dengue epidemic occurred in Rio Grande do Norte, a State in north-east Brazil. The cocirculation of dengue virus type 1 and dengue virus type 2 was demonstrated by virus isolation in Aedes albopictus clone C6/36 cell-line and by reverse transcriptase-polymerase chain reaction (RT-PCR). IgM capture enzyme-linked immunosorbent assay confirmed 52.3% of the 8105 studied cases and dengue antigen was demonstrated by immunohistochemical reaction on hepatocytes from 2 out of 5 fatal cases studied. Individual risk factors for development of dengue haemorrhagic fever/dengue shock syndrome, such as hypertension, diabetes mellitus and bronchial asthma, are discussed.

引用

页码：247 / 249

页数：3

共 24 条

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