A novel oxidative transformation of α-aminonitriles to amides

被引：10

作者：

Yokoshima, S ^{[1
]}

Kubo, T ^{[1
]}

Tokuyama, H ^{[1
]}

Fukuyama, T ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

来源：

CHEMISTRY LETTERS | 2002年 / 02期

关键词：

D O I：

10.1246/cl.2002.122

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel oxidative transformation of alpha-aminonitriles to amides is reported. Oxidation of alpha-aminonitriles with peracid, followed by basic treatment affords, amides in good yields. A mechanistic aspect of this transformation is also discussed.

引用

页码：122 / 123

页数：2

共 9 条

[1]

AGER DJ, 1987, UMPOLED SYNTHONS

[2]

CHUANG TH, 1990, SYNLETT, P733

[3] STEREOCONTROLLED TOTAL SYNTHESIS OF (+/-)-QUINOCARCIN [J].

FUKUYAMA, T ;

NUNES, JJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (15) :5196-5198

[4]

Grierson D., 1990, Org. React, V39, P85, DOI [10.1002/0471264180.or039.02, DOI 10.1002/0471264180.OR039.02]

[5]

HARUSAWA S, 1979, TETRAHEDRON LETT, P4663

[6]

Tokuyama H, 2000, SYNTHESIS-STUTTGART, P1299

[7]

Yang CC, 1997, SYNLETT, P812

[8]

Yokoshima S, 2000, ANGEW CHEM INT EDIT, V39, P4073, DOI 10.1002/1521-3773(20001117)39:22<4073::AID-ANIE4073>3.0.CO

[9]

2-V

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