Assessment of double-barrelled heck cyclizations as a means for construction of the 14-phenyl-8,9-dihydro-6H-[1]benzopyrano[4′,3′:4,5]pyrrolo[2,1-a]isoquinolin-6-one core associated with certain members of the lamellarin class of marine natural product

被引：49

作者：

Banwell, MG ^{[1
]}

Flynn, BL ^{[1
]}

Hockless, DCR ^{[1
]}

Longmore, RW ^{[1
]}

Rae, AD ^{[1
]}

机构：

[1] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 0200, Australia

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1999年 / 52卷 / 08期

关键词：

D O I：

10.1071/CH99021

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The 1,2,4-trisubstituted pyrrole (4), which is readily prepared from pyrrole itself, undergoes double-barrelled Heck cyclizations to give, inter alia, compounds (3) and (17) for which crystal structures have been determined. Product (3) constitutes the core associated with several key members, e.g. (1) and (2), of the lamellarin class of marine alkaloid.

引用

页码：755 / 765

页数：11

共 46 条

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