Protective immunity against hepatitis C virus infection

被引:32
作者
Elliott, Lisa N.
Lloyd, Andrew R.
Ziegler, John B.
Ffrench, Rosemary A.
机构
[1] Burnet Inst, Viral Immunol Grp, Melbourne, Vic, Australia
[2] Univ New S Wales, Sch Womens & Childrens Hlth, Sydney, NSW, Australia
[3] Univ New S Wales, Sch Med Sci, Inflammatory Dis Res Unit, Sydney, NSW, Australia
关键词
cellular immunity; hepatitis C virus; vaccination;
D O I
10.1111/j.1440-1711.2006.01427.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 [细胞生物学]; 090102 [作物遗传育种];
摘要
There is increasing evidence that a small percentage of individuals exposed to the hepatitis C virus have the capacity to generate a strong cellular immune response against the virus and avoid persistent infection, and perhaps do so repeatedly after re-exposure. This article reviews the evidence that the responses identified in this unique group of individuals represent the protective immunity that will need to be elicited by hepatitis C virus vaccines.
引用
收藏
页码:239 / 249
页数:11
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