CARPET: a web-based package for the analysis of ChIP-chip and expression tiling data

被引:21
作者
Cesaroni, Matteo [1 ]
Cittaro, Davide [2 ]
Brozzi, Alessandro [1 ]
Pelicci, Pier Giuseppe [1 ]
Luzi, Lucilla [3 ]
机构
[1] European Inst Oncol, Dept Expt Oncol, I-20141 Milan, Italy
[2] Cogentech, Consortium Genom Technol, I-20139 Milan, Italy
[3] FIRC Inst Mol Oncol Fdn, IFOM, I-20139 Milan, Italy
关键词
D O I
10.1093/bioinformatics/btn542
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
CARPET (collection of automated routine programs for easy tiling) is a set of Perl, Python and R scripts, integrated on the Galaxy2 web-based platform, for the analysis of ChIP-chip and expression tiling data, both for standard and custom chip designs. CARPET allows rapid experimental data entry, simple quality control, normalization, easy identification and annotation of enriched ChIP-chip regions, detection of the absolute or relative transcriptional status of genes assessed by expression tiling experiments and, more importantly, it allows the integration of ChIP-chip and expression data. Results can be visualized instantly in a genomic context within the UCSC genome browser as graph-based custom tracks through Galaxy2. All generated and uploaded data can be stored within sessions and are easily shared with other users.
引用
收藏
页码:2918 / 2920
页数:3
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