Vaccines and antibodies in the prevention and treatment of sepsis

被引：3

作者：

Bhattacharjee, AK ^{[1
]}

Cross, AS

机构：

[1] Walter Reed Army Med Ctr, Walter Reed Army Inst Res, Dept Bacterial Dis, Washington, DC 20307 USA

[2] Univ Maryland, Sch Med, Dept Med, Div Infect Dis, Baltimore, MD 21201 USA

[3] UMD Sch Med, Greenebaum Canc Ctr, Program Infect Dis, Baltimore, MD USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 1999年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0891-5520(05)70079-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Antibodies to various core glycolipid antigens have been shown to correlate with survival from Gram-negative sepsis. Recent preclinical data also support efficacy of the anti-core glycolipid antibodies in the treatment of sepsis. Failure of some of the previous clinical trials with anti-core glycolipid antibody was probably due to inadequate levels of antibody in those preparations. Future clinical trials must ensure that sufficient amounts of anti-core glycolipid antibodies are present in the circulation of patients with sepsis.

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页码：355 / +

页数：16

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