The exchange of one single amino acid at position 71 of the DR4 β-chain leads to significant differences in antigen processing and presentation of a human autoantigen chaperoned by a member of the HSP70 family

被引:2
作者
Roth, S. [1 ]
Willcox, N. [2 ]
Mayer, M. P. [3 ]
Melchers, I. [1 ]
机构
[1] Univ Med Ctr, Clin Res Unit Rheumatol, Freiburg, Germany
[2] Univ Oxford, Inst Mol Med, Neurosci Grp, Oxford OX1 2JD, England
[3] Univ Freiburg, Inst Biochem & Mol Biol, Freiburg, Germany
关键词
Rheumatoid Arthritis; Shared Epitope; HSP70 Family; Common Amino Acid; DRB1 Gene;
D O I
10.1186/ar278
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
P109
引用
收藏
页数:1
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