Desulfurization of sultones with simultaneous methylenation

被引：17

作者：

Metz, P

Seng, D

Plietker, B

机构：

[1] Organisch-Chemisches Institut, Universität Münster, D-48149 Münster

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 22期

关键词：

D O I：

10.1016/0040-4039(96)00728-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Desulfurization of the delta-sultones 2 with simultaneous formation of an exocyclic defin is achieved by alkylation of 2 with (iodomethyl)trimethylsilane and subsequent treatment of the resultant products 7 with tetra-n-butylammonium fluoride. Application of this two-step procedure to sultone 8 leads to 1,3-diene 10, an intermediate for the synthesis of the highly oxygenated 1,10-seco-eudesmanolides eriolanin and eriolangin. Copyright (C) 1996 Elsevier Science Ltd

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页码：3841 / 3844

页数：4

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