Increased risk of NASH in patients carrying the C(-159) T polymorphism in the CD14 gene promoter region

被引：27

作者：

Brun, P.

Castagliuolo, I.

Floreani, A. R.

Buda, A.

Blasone, L.

Palu, G.

Martines, D.

机构：

[1] Univ Padua, Sch Pharm, Dept Histol Microbiol & Med Biotechnol, I-35121 Padua, Italy

[2] Univ Padua, Dept Gastroenterol Surg, Padua, Italy

来源：

GUT | 2006年 / 55卷 / 08期

关键词：

D O I：

10.1136/gut.2006.093336

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：1212 / 1212

页数：1

共 9 条

[1] TLR4 mutations are associated with endotoxin hyporesponsiveness in humans [J].

Arbour, NC ;

Lorenz, E ;

Schutte, BC ;

Zabner, J ;

Kline, JN ;

Jones, M ;

Frees, K ;

Watt, JL ;

Schwartz, DA .

NATURE GENETICS, 2000, 25 (02) :187-+

[2] Exposure to bacterial cell wall products triggers an inflammatory phenotype in hepatic stellate cells [J].

Brun, P ;

Castagliuolo, I ;

Pinzani, M ;

Palù, G ;

Martines, D .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2005, 289 (03) :G571-G578

[3] Is obesity an inflammatory condition? [J].

Das, UN .

NUTRITION, 2001, 17 (11-12) :953-966

[4] Promoter polymorphism of the CD14 endotoxin receptor gene as a risk factor for alcoholic liver disease [J].

Järveläinen, HA ;

Orpana, A ;

Perola, M ;

Savolainen, VT ;

Karhunen, PJ ;

Lindros, KO .

HEPATOLOGY, 2001, 33 (05) :1148-1153

[5] HEPATIC-INJURY ASSOCIATED WITH SMALL-BOWEL BACTERIAL OVERGROWTH IN RATS IS PREVENTED BY METRONIDAZOLE AND TETRACYCLINE [J].

LICHTMAN, SN ;

KEKU, J ;

SCHWAB, JH ;

SARTOR, RB .

GASTROENTEROLOGY, 1991, 100 (02) :513-519

[6] Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in non-alcoholic steatohepatitis [J].

Namikawa, C ;

Shu-Ping, Z ;

Vyselaar, JR ;

Nozaki, Y ;

Nemoto, Y ;

Ono, M ;

Akisawa, N ;

Saibara, T ;

Hiroi, M ;

Enzan, H ;

Onishil, S .

JOURNAL OF HEPATOLOGY, 2004, 40 (05) :781-786

[7] Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells [J].

Paik, YH ;

Schwabe, RF ;

Bataller, R ;

Russo, MP ;

Jobin, C ;

Brenner, DA .

HEPATOLOGY, 2003, 37 (05) :1043-1055

[8] The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor α in the pathogenesis of non-alcoholic steatohepatitis [J].

Wigg, AJ ;

Roberts-Thomson, IC ;

Dymock, RB ;

McCarthy, PJ ;

Grose, RH ;

Cummins, AG .

GUT, 2001, 48 (02) :206-211

[9]

ZHANG DE, 1994, J BIOL CHEM, V269, P11425

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