Induction of CYP1A by various benzimidazoles and its significance in administrative drug regulation

被引：6

作者：

Kleeberg, U

Frötschl, R

Krusekopf, S

Brockmöller, J

Roots, I

Ruckpaul, K

Hildebrandt, AG

机构：

[1] Fed Inst Drugs & Med Devices BfArM, D-13353 Berlin, Germany

[2] Humboldt Univ, Univ Clin Charite, Inst Clin Pharmacol, D-10098 Berlin, Germany

[3] Max Delbruck Ctr Mol Med, D-13125 Berlin, Germany

来源：

DRUG METABOLISM REVIEWS | 1999年 / 31卷 / 02期

关键词：

benzimidazoles; H/K-ATPase inhibitors; cytochromes; (CYP1A; CYP1B1); induction; transcription (RNA polymerase; mRNA); cell lines (HEPG2; HUH7; HELA);

D O I：

10.1081/DMR-100101925

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：381 / 392

页数：12

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