Cyclodextrin-accelerated cleavage of phenyl esters: is it the 2-hydroxy or the 3-hydroxy that promotes the acyl transfer?

被引：14

作者：

Fukudome, M ^{[1
]}

Okabe, Y ^{[1
]}

Yuan, DQ ^{[1
]}

Fujita, K ^{[1
]}

机构：

[1] Nagasaki Univ, Fac Pharmaceut Sci, Nagasaki 8528521, Japan

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 11期

关键词：

D O I：

10.1039/a902123j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Both 2- and 3-monothiocyclodextrins have been synthesized and used in probing the mechanism of cyclodextrin-mediated cleavage of phenyl esters, showing that the 3-thiols are much more effective than the 2-thiols in promoting the acyl transfer.

引用

页码：1045 / 1046

页数：2

共 18 条

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