Regulation of intestinal homeostasis and immunity with probiotic lactobacilli

被引：349

作者：

van Baarlen, Peter ^{[1
]}

Wells, Jerry M. ^{[1
]}

Kleerebezem, Michiel ^{[1
]}

机构：

[1] Wageningen Univ, Host Microbe Interact Grp, NL-6708 WD Wageningen, Netherlands

来源：

TRENDS IN IMMUNOLOGY | 2013年 / 34卷 / 05期

关键词：

gastrointestinal health; host-microbe interactions; probiotics; immunomodulation; personalization; resilience; WALL TEICHOIC-ACID; GUT MICROBIOTA; RHAMNOSUS GG; T-CELLS; LIPOTEICHOIC ACID; FUNCTIONAL-ANALYSIS; EPITHELIAL BARRIER; CONTROLLED-TRIALS; DENDRITIC CELL; IN-VIVO;

D O I：

10.1016/j.it.2013.01.005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

The gut microbiota provide important stimuli to the human innate and adaptive immune system and co-mediate metabolic and immune homeostasis. Probiotic bacteria can be regarded as part of the natural human microbiota, and have been associated with improving homeostasis, albeit with different levels of success. Composition of microbiota, probiotic strain identity, and host genetic differences may account for differential modulation of immune responses by probiotics. Here, we review the mechanisms of immunomodulating capacities of specific probiotic strains, the responses they can induce in the host, and how microbiota and genetic differences between individuals may co-influence host responses and immune homeostasis.

引用

收藏

页码：208 / 215

页数：8

相关论文

共 83 条

[1]

Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut [J].

Artis, David .

NATURE REVIEWS IMMUNOLOGY, 2008, 8 (06) :411-420

[2]

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species [J].

Atarashi, Koji ;

Tanoue, Takeshi ;

Shima, Tatsuichiro ;

Imaoka, Akemi ;

Kuwahara, Tomomi ;

Momose, Yoshika ;

Cheng, Genhong ;

Yamasaki, Sho ;

Saito, Takashi ;

Ohba, Yusuke ;

Taniguchi, Tadatsugu ;

Takeda, Kiyoshi ;

Hori, Shohei ;

Ivanov, Ivaylo I. ;

Umesaki, Yoshinori ;

Itoh, Kikuji ;

Honda, Kenya .

SCIENCE, 2011, 331 (6015) :337-341

[3]

Lactobacillus plantarum possesses the capability for wall teichoic acid backbone alditol switching [J].

Bron, Peter A. ;

Tomita, Satoru ;

van Swam, Iris I. ;

Remus, Daniela M. ;

Meijerink, Marjolein ;

Wels, Michiel ;

Okada, Sanae ;

Wells, Jerry M. ;

Kleerebezem, Michiel .

MICROBIAL CELL FACTORIES, 2012, 11

[4]

Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa [J].

Bron, Peter A. ;

van Baarlen, Peter ;

Kleerebezem, Michiel .

NATURE REVIEWS MICROBIOLOGY, 2012, 10 (01) :66-U90

[5]

Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function [J].

Cario, E. ;

Gerken, G. ;

Podolsky, D. K. .

GASTROENTEROLOGY, 2007, 132 (04) :1359-1374

[6]

Genetic and Biochemical Characterization of the Cell Wall Hydrolase Activity of the Major Secreted Protein of Lactobacillus rhamnosus GG [J].

Claes, Ingmar J. J. ;

Schoofs, Geert ;

Regulski, Krzysztof ;

Courtin, Pascal ;

Chapot-Chartier, Marie-Pierre ;

Rolain, Thomas ;

Hols, Pascal ;

von Ossowski, Ingemar ;

Reunanen, Justus ;

de Vos, Willem M. ;

Palva, Airi ;

Vanderleyden, Jos ;

De Keersmaecker, Sigrid C. J. ;

Lebeer, Sarah .

PLOS ONE, 2012, 7 (02)

[7]

Absence of serotype-specific surface antigen and altered teichoic acid glycosylation among epidemic-associated strains of Listeria monocytogenes [J].

Clark, EE ;

Wesley, I ;

Fiedler, F ;

Promadej, N ;

Kathariou, S .

JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (10) :3856-3859

[8]

The intestinal microbiota and chronic disorders of the gut [J].

DuPont, Andrew W. ;

DuPont, Herbert L. .

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2011, 8 (09) :523-531

[9]

Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide [J].

Fernandez, Elise Macho ;

Valenti, Veronique ;

Rockel, Christoph ;

Hermann, Corinna ;

Pot, Bruno ;

Boneca, Ivo Gomperts ;

Grangette, Corinne .

GUT, 2011, 60 (08) :1050-1059

[10]

Recommendations for Probiotic Use-2011 Update [J].

Floch, Martin H. ;

Walker, W. Allan ;

Madsen, Karen ;

Sanders, Mary Ellen ;

Macfarlane, George T. ;

Flint, Harry J. ;

Dieleman, Levinus A. ;

Ringel, Yehuda ;

Guandalini, Stefano ;

Kelly, Ciaran P. ;

Brandt, Lawrence J. .

JOURNAL OF CLINICAL GASTROENTEROLOGY, 2011, 45 :S168-S171

← 1 2 3 4 5 6 7 8 9 →