Asymmetric deactivation of racemic BINAP-Ru(II) catalysts through complete enantiomer discrimination by dimethylbinaphthylamine:: Highly enantioselective hydrogenation of olefin and β-keto ester

被引：16

作者：

Mikami, K ^{[1
]}

Yusa, Y ^{[1
]}

Korenaga, T ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Appl Chem, Tokyo 1528552, Japan

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 10期

关键词：

D O I：

10.1021/ol0256567

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] 3,3'-Dimethyl-2,2'-diamino-1,1'-binaphthyl (DM-DABN) is designed as a "chiral poison" (deactivator) for complete enantiomer resolution of racemic BINAP-Ru(II) catalysts in a highly enantioselective hydrogenation of beta-keto ester and kinetic resolution of racemic 2-cyclohexen-1-ol.

引用

页码：1643 / 1645

页数：3

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