Pin-ning down immune responses to RNA viruses

被引:9
作者
Goutagny, Nadege [1 ]
Severa, Martina [1 ]
Fitzgerald, Katherine A. [1 ]
机构
[1] Univ Massachusetts, Sch Med, Dept Med, Div Infect Dis & Immunol, Worcester, MA 01605 USA
关键词
D O I
10.1038/ni0606-555
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To prevent RNA virus-dependent tissue damage caused by interferon-regulatory factor 3 (IRF3)-induced type I interferons, proteasome-dependent destruction of IRF3 is orchestrated by the cytoplasmic prolyl isomerase Pin1.
引用
收藏
页码:555 / 557
页数:4
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