Probing meiotic recombination decisions

被引:8
作者
Roig, Ignasi [1 ]
Keeney, Scott [1 ,2 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Program Mol Biol, New York, NY 10065 USA
[2] Mem Sloan Kettering Canc Ctr, Howard Hughes Med Inst, New York, NY 10065 USA
关键词
D O I
10.1016/j.devcel.2008.08.009
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Meiotic recombination promotes genetic variation by mixing parental alleles. Two recent studies, one in this issue of Developmental Cell, have applied microarray-based methods that allow analysis of nearly all of the recombination events occurring in a single meiosis. These data provide insights into the molecular "decisions" that control the outcome of the recombination process.
引用
收藏
页码:331 / 332
页数:2
相关论文
共 10 条
[1]   Early decision: Meiotic crossover interference prior to stable strand exchange and synapsis [J].
Bishop, DK ;
Zickler, D .
CELL, 2004, 117 (01) :9-15
[2]   Mapping meiotic single-strand DNA reveals a new landscape of DNA double-strand breaks in Saccharomyces cerevisiae [J].
Buhler, Cyril ;
Borde, Valerie ;
Lichten, Michael .
PLOS BIOLOGY, 2007, 5 (12) :2797-2808
[3]   Global analysis of the meiotic crossover landscape [J].
Chen, Stacy Y. ;
Tsubouchi, Tomomi ;
Rockmill, Beth ;
Sandler, Jay S. ;
Richards, Daniel R. ;
Vader, Gerben ;
Hochwagen, Andreas ;
Roeder, G. Shirleen ;
Fung, Jennifer C. .
DEVELOPMENTAL CELL, 2008, 15 (03) :401-415
[4]   The origin of human aneuploidy: where we have been, where we are going [J].
Hassold, Terry ;
Hall, Heather ;
Hunt, Patricia .
HUMAN MOLECULAR GENETICS, 2007, 16 :R203-R208
[5]  
Keeney Scott, 2008, V2, P81, DOI 10.1007/7050_2007_026
[6]   ZMM proteins during meiosis:: Crossover artists at work [J].
Lynn, Audrey ;
Soucek, Rachel ;
Boerner, G. Valentin .
CHROMOSOME RESEARCH, 2007, 15 (05) :591-605
[7]   High-resolution mapping of meiotic crossovers and non-crossovers in yeast [J].
Mancera, Eugenio ;
Bourgon, Richard ;
Brozzi, Alessandro ;
Huber, Wolfgang ;
Steinmetz, Lars M. .
NATURE, 2008, 454 (7203) :479-U1
[8]   Crossover homeostasis in yeast meiosis [J].
Martini, Emmanuelle ;
Diaz, Robert L. ;
Hunter, Neil ;
Keeney, Scott .
CELL, 2006, 126 (02) :285-295
[9]   A synaptonemal complex protein promotes homology-independet centromere coupling [J].
Tsubouchi, T ;
Roeder, GS .
SCIENCE, 2005, 308 (5723) :870-873
[10]   Direct allelic variation scanning of the yeast genome [J].
Winzeler, EA ;
Richards, DR ;
Conway, AR ;
Goldstein, AL ;
Kalman, S ;
McCullough, MJ ;
McCusker, JH ;
Stevens, DA ;
Wodicka, L ;
Lockhart, DJ ;
Davis, RW .
SCIENCE, 1998, 281 (5380) :1194-1197