Is there a link between adult neurogenesis and learning?

被引:419
作者
Leuner, B
Gould, E
Shors, TJ
机构
[1] Rutgers State Univ, Dept Psychol, Princeton, NJ 08544 USA
[2] Rutgers State Univ, Ctr Collaborat Neurosci, Princeton, NJ 08544 USA
[3] Princeton Univ, Dept Psychol, Princeton, NJ 08544 USA
关键词
dentate gyrus; water maze; hippocampus; memory; BrdU; eyeblink conditioning;
D O I
10.1002/hipo.20153
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
During the past several years, evidence has accumulated suggesting a relationship between newly born cells in the hippocampus and various types of learning and memory. However, most of the evidence is correlational and some of it does not agree. This review discusses both sides of this issue, considering the effects of learning on the production of new neurons in the dentate gyrus and the question of whether newly born cells participate in learning and memory. (c) 2006 Wiley-Liss Inc.
引用
收藏
页码:216 / 224
页数:9
相关论文
共 101 条
[1]  
Abrous DN, 2002, J NEUROSCI, V22, P3656
[2]   A facilitative role for corticosterone in the acquisition of a spatial task under moderate stress [J].
Akirav, I ;
Kozenicky, M ;
Tal, D ;
Sandi, C ;
Venero, C ;
Richter-Levin, G .
LEARNING & MEMORY, 2004, 11 (02) :188-195
[3]   AUTORADIOGRAPHIC AND HISTOLOGICAL EVIDENCE OF POSTNATAL HIPPOCAMPAL NEUROGENESIS IN RATS [J].
ALTMAN, J ;
DAS, GD .
JOURNAL OF COMPARATIVE NEUROLOGY, 1965, 124 (03) :319-&
[4]   BIRTH OF PROJECTION NEURONS IN ADULT AVIAN BRAIN MAY BE RELATED TO PERCEPTUAL OR MOTOR LEARNING [J].
ALVAREZBUYLLA, A ;
KIRN, JR ;
NOTTEBOHM, F .
SCIENCE, 1990, 249 (4975) :1444-1446
[5]   Spatial learning affects immature granule cell survival in adult rat dentate gyrus [J].
Ambrogini, P ;
Cuppini, R ;
Cuppini, C ;
Ciaroni, S ;
Cecchini, T ;
Ferri, P ;
Sartini, S ;
Del Grande, P .
NEUROSCIENCE LETTERS, 2000, 286 (01) :21-24
[6]   Learning may reduce neurogenesis in adult rat dentate gyrus [J].
Ambrogini, P ;
Orsini, L ;
Mancini, C ;
Ferri, P ;
Ciaroni, S ;
Cuppini, R .
NEUROSCIENCE LETTERS, 2004, 359 (1-2) :13-16
[7]   Morpho-functional characterization of neuronal cells at different stages of maturation in granule cell layer of adult rat dentate gyrus [J].
Ambrogini, P ;
Lattanzi, D ;
Ciuffoli, S ;
Agostini, D ;
Bertini, L ;
Stocchi, V ;
Santi, S ;
Cuppini, R .
BRAIN RESEARCH, 2004, 1017 (1-2) :21-31
[8]   Recruitment and replacement of hippocampal neurons in young and adult chickadees: An addition to the theory of hippocampal learning [J].
Barnea, A ;
Nottebohm, F .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (02) :714-718
[9]   SEASONAL RECRUITMENT OF HIPPOCAMPAL-NEURONS IN ADULT FREE-RANGING BLACK-CAPPED CHICKADEES [J].
BARNEA, A ;
NOTTEBOHM, F .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (23) :11217-11221
[10]   Selective enhancement of spatial learning under chronic psychosocial stress [J].
Bartolomucci, A ;
de Biurrun, G ;
Czéh, B ;
van Kampen, M ;
Fuchs, E .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2002, 15 (11) :1863-1866