The Nail as a Musculoskeletal Appendage - Implications for an Improved Understanding of the Link between Psoriasis and Arthritis

被引：137

作者：

McGonagle, Dennis ^{[1
,2
]}

Tan, Ai Lyn ^{[2
]}

Benjamin, Michael ^{[3
]}

机构：

[1] Chapel Allerton Hosp, Acad Unit Musculoskeletal Dis, Leeds LS7 4SA, W Yorkshire, England

[2] Univ Leeds, Acad Unit Musculoskeletal Dis, Leeds, W Yorkshire, England

[3] Cardiff Univ, Sch Biosci, Cardiff, S Glam, Wales

来源：

DERMATOLOGY | 2009年 / 218卷 / 02期

关键词：

Nail disease; Psoriasis; Psoriatic arthritis; Enthesis; Nail anchorage; JOINT DISEASE; ENTHESIS; OSTEOARTHRITIS; ENTHESOPATHY; ARTHROPATHY; DISORDERS; SYNOVITIS; MATRIX;

D O I：

10.1159/000182250

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100227 [皮肤病学];

摘要：

The nail is considered to be a specialised modification of the skin - an 'epidermal appendage'. However, the phrase 'hanging on by your fingernails' belies a vital aspect of nail micro-anatomy that has been overlooked, namely that the nail is functionally integrated with the musculoskeletal system. The current article reviews how the nail is functionally linked to the distal phalanx and several distal interphalangeal joint structures, including extensor tendon fibres and the collateral ligaments. New histological images exploring this link are provided. The extensor tendon in particular continues from its bony insertion to envelop the nail root, and the collateral ligaments form an integrated network on the sides of the joint, helping to anchor the nail margins. This virtual continuum of connective tissue structures merges with a thick periosteum on the distal phalanx and with the numerous cutaneous ligaments that anchor the fatty pads of the finger pulp to the skin. Copyright (C) 2008 S. Karger AG, Basel

引用

页码：97 / 102

页数：6

共 23 条

[1]

Microdamage and altered vascularity at the enthesis-bone interface provides an anatomic explanation for bone involvement in the HLA-B27-associated spondylarthritides and allied disorders [J].