The ketogenic diet - update on recent clinical trials

被引：26

作者：

Cross, J. Helen ^{[1
,2
,3
]}

Neal, Elizabeth G. ^{[2
]}

机构：

[1] UCL, Inst Child Hlth, Wolfson Ctr, Neurosci Unit, London WC1N 2AP, England

[2] Great Ormond St Hosp Sick Children, London WC1N 3JH, England

[3] London & Natl Ctr Young People Epilepsy, Surrey, England

来源：

EPILEPSIA | 2008年 / 49卷

关键词：

Clinical trials; Ketogenic diet; Epilepsy; Childhood;

D O I：

10.1111/j.1528-1167.2008.01822.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The ketogenic diet (KD) has been used in the treatment of epilepsy for almost 100 years. Several cohort studies have emphasized its possible benefit, although use became less at the introduction of anticonvulsant medication. However, the KD has regained recognition over the past 15 years. Resources remain scarce and its availability for children may be limited. One argument has been the lack of evidence from suitably designed trials. Systematic reviews and meta-analyses have revealed that studies are limited to class 3 and 4 data. A recently published randomized controlled trial has shown that the benefit of the KD is equivalent to any of the new anticonvulsant medications, emphasizing the need for more resources to ensure greater diet availability.

引用

页码：6 / 10

页数：5

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