Cellular polarization induced by chemokines: A mechanism for leukocyte recruitment?

被引:96
作者
delPozo, MA
SanchezMateos, P
SanchezMadrid, F
机构
来源
IMMUNOLOGY TODAY | 1996年 / 17卷 / 03期
关键词
D O I
10.1016/0167-5699(96)80604-9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
chemokines are known to induce leukocyte adhesion to the endothelium and emigration into tissues. Here, Miguel Angel del Pozo and colleagues discuss how these molecules also appear to regulate the redistribution of cell adhesion receptors. Recruitment of adhesion molecules towards a cellular uropod in response to chemokines may represent a novel cooperative mechanism in the recruitment of leukocytes to sites of inflammation.
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页码:127 / 131
页数:5
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