Quality of life in patients with early, moderate and advanced glaucoma

Purpose To evaluate the quality of life in glaucomatous patients using two different questionnaires: the medical outcomes study 36-item short-form health survey (MOS SF-36) and Viswanathan et al's questionnaire and to compare these two questionnaires. Methods Seventy-seven patients with glaucoma were consecutively selected. Two force-choice questionnaires were administered to each patient. Viswanathan et al's questionnaire was related to visual disability and the second was related to the quality of life from the MOS 36-item short-form health survey. Both questionnaires were evaluated among all the considered patients and the results were compared. Then the questionnaire which did the best evaluation was used to test the quality of life in three different subgroups based on the mean deviation of the worse eye. Mann-Whitney non parametric test and Spearman's r coefficient were used and a P value less than 0.05 was considered to be statistically significant. A linear regression model was used. Results In the entire group (n=77) the Mean Deviation (MD) was -6.5+/-6.8 dB (mean standard deviation) and Corrected Pattern Standard Deviation (CPSD) was 4.7+/-4.1 dB. The score of the Viswanathan et al's questionnaire was 8.3+/-2.4, while MOS SF-36 score ranged from 60.5% to 100% (mean score %). A significant (P<0.0001) correlation was found between the score of the Viswanathan et al's questionnaire and MD (r=0.79), Pattern Standard Deviation (PSD) (r=-0.68) and CPSD (r=-0.61). Conclusion Viswanathan et al's questionnaire was more useful than MOS SF-36, both for the score and for the velocity to use. Furthermore Viswanathan et al's questionnaire was more significantly correlated to visual field MD.