Systemic lupus erythematosus with acanthosis nigricans, hyperpigmentation, and insulin receptor antibody

被引:15
作者
Baird, JS [1 ]
Johnson, JL [1 ]
ElliottMills, D [1 ]
Opas, LM [1 ]
机构
[1] UNIV SO CALIF,SCH MED,LOS ANGELES,CA 90089
关键词
acanthosis nigricans; hyperpigmentation; lupus erythematosus; systemic; insulin resistance;
D O I
10.1177/096120339700600311
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acanthosis nigricans, insulin receptor antibody, and systemic lupus erythematosus are associated in the potentially lethal syndrome of type B insulin resistance. Hyperpigmentation has been reported rarely, while glucose intolerance is common in these patients. We report an adolescent girl with acanthosis nigricans, hyperpigmentation, insulin receptor antibody, and systemic lupus erythematosus without glucose intolerance. Insulin resistance may be mild or transient in some patients with type B insulin resistance. Resolution of skin lesions was noted during therapy of SLE, and was associated with disappearance of insulin receptor antibody.
引用
收藏
页码:275 / 278
页数:4
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