Assessment and Modulation of Neural Plasticity in Rehabilitation With Transcranial Magnetic Stimulation

被引：78

作者：

Bashir, Shahid ^{[3
]}

Mizrahi, Ilan ^{[3
]}

Weaver, Kayleen ^{[1
]}

Fregni, Felipe ^{[1
]}

Pascual-Leone, Alvaro ^{[2
,3
]}

机构：

[1] Harvard Univ, Sch Med, Lab Neuromodulot, Spaulding Rehabil Hosp, Boston, MA 02115 USA

[2] Univ Autonoma Barcelona, Inst Guttmann, Barcelona, Spain

[3] Harvard Univ, Berenson Allen Ctr Noninvas Brain Stimulat, Dept Neurol, Beth Israel Deaconess Med Ctr,Med Sch, Boston, MA 02215 USA

来源：

PM&R | 2010年 / 2卷 / 12期

关键词：

D O I：

10.1016/j.pmrj.2010.10.015

中图分类号：

R49 [康复医学];

学科分类号：

100215 ;

摘要：

Despite intensive efforts to improve outcomes after acquired brain injury, functional recovery is often limited. One reason for this limitation is the challenge in assessing and guiding plasticity after brain injury. In this context, transcranial magnetic stimulation (TMS), a noninvasive tool of brain stimulation, could play a major role. TMS has been shown to be a reliable tool for measuring plastic changes in the motor cortex associated with interventions in the motor system, such as motor training and motor cortex stimulation. In addition, as illustrated by the experience in promoting recovery from stroke, TMS is a promising therapeutic tool to minimize motor, speech, cognitive, and mood deficits. In this review, we will focus on stroke to discuss how TMS can provide insights into the mechanisms of neurologic recovery and how it can be used for measurement and modulation of plasticity after an acquired brain insult. PM R 2010;2:S253-S268

引用

页码：S253 / S268

页数：16

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