Synthesis and non-covalent functionalization of carbon nanotubes rings: new nanomaterials with lectin affinity

被引：13

作者：

Assali, Mohyeddin ^{[1
]}

Pernia Leal, Manuel ^{[1
]}

Fernandez, Inmaculada ^{[2
]}

Khiar, Noureddine ^{[1
]}

机构：

[1] Univ Seville, CSIC, Inst Invest Quim, Seville 41092, Spain

[2] Univ Seville, Dept Quim Organ & Farmaceut, E-41012 Seville, Spain

来源：

NANOTECHNOLOGY | 2013年 / 24卷 / 08期

关键词：

SELECTIN-CARBOHYDRATE INTERACTIONS; NANOTECHNOLOGY; NANOPARTICLES; THERAPEUTICS; TRANSPORTERS; PROTEINS; DELIVERY; CANCER; CELLS;

D O I：

10.1088/0957-4484/24/8/085604

中图分类号：

TB3 [工程材料学];

学科分类号：

082905 [生物质能源与材料];

摘要：

We present a mild and practical carbon nanotubes rings (CNRs) synthesis from non-covalent functionalized and water-soluble linear single-wall carbon nanotubes. The hemi-micellar-supramolecular self-organization of lactose-based glycolipid 1 on the ring surface, followed by photo-polymerization of the diacetylenic function triggered by UV light afforded the first water-soluble and biocompatible CNRs. The obtained donut-like nanoconstructs expose a high density of lactose moieties on their surface, and are able to engage specific interactions with Arachis hypogea lectin similar to glycoconjugates on the cell membrane.

引用

页数：12

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