Iridium-catalyzed H/D exchange into organic compounds in water

被引：176

作者：

Klei, SR

Golden, JT

Tilley, TD ^{[1
]}

Bergman, RG

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, CNDOS, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Chem Sci, Berkeley, CA 94720 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 10期

关键词：

D O I：

10.1021/ja017219d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The air-stable complex Cp*(PMe3)IrCl2 efficiently catalyzes the exchange of deuterium from D2O into both activated and unactivated C-H bonds of organic molecules without added acid or stabilizers. Selectivity is observed in many cases, with activation of primary C-H bonds occurring preferentially. A number of new stoichiometric transformations involving the iridiym catalyst precursor are also presented, including an ozidation-decarbonylation reaction with primary alcohols. Copyright © 2002 American Chemical Society.

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页码：2092 / 2093

页数：2

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