Nicolaus Copernicus and the rapid vascular responses to aldosterone

被引:21
作者
Barton, Matthias [1 ]
Meyer, Matthias R. [2 ]
机构
[1] Univ Zurich, Mol Internal Med, CH-8006 Zurich, Switzerland
[2] Univ Hosp Bern, Dept Cardiol, Bern, Switzerland
关键词
membrane receptor; non-genomic; steroid receptor; GPR30; aldosterone; RECEPTOR; ACTIVATION; CELLS; GPER;
D O I
10.1016/j.tem.2015.05.005
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
For decades, rapid steroid responses initiated by membrane receptors have been a primary research focus. G protein-coupled estrogen receptor (GPER) is activated by 17 beta-estradiol and participates in functional crosstalk with other steroid receptors. With reference to the physician and astronomer Nicolaus Copernicus (1473-1543), who used rigorous scientific approaches to shift paradigms and change dogma, we discuss whether GPER can also be considered an aldosterone receptor.
引用
收藏
页码:396 / 398
页数:3
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