SONOGRAPHIC AND PATHOLOGIC IMAGE ANALYSIS OF PURE MUCINOUS CARCINOMA OF THE BREAST

被引：49

作者：

Kaoku, Setsuko ^{[1
]}

Konishi, Eiichi ^{[1
]}

Fujimoto, Yasuhisa ^{[2
]}

Tohno, Eriko ^{[3
]}

Shiina, Tsuyoshi ^{[4
]}

Kondo, Kengo ^{[4
]}

Yamazaki, Sanae ^{[1
]}

Kajihara, Mariko ^{[5
]}

Shinkura, Nobuhiko ^{[5
]}

Yanagisawa, Akio ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Dept Surg Pathol, Grad Sch Med Sci, Kyoto 6028566, Japan

[2] Tachibana Hosp, Dept Breast Surg, Himeji, Hyogo, Japan

[3] Total Hlth Evaluat Ctr Tsukuba, Ibaraki, Japan

[4] Kyoto Univ, Grad Sch Med, Kyoto, Japan

[5] Sawai Mem Clin, Kyoto Breast Ctr, Kyoto, Japan

来源：

ULTRASOUND IN MEDICINE AND BIOLOGY | 2013年 / 39卷 / 07期

关键词：

Mucinous carcinoma; Breast; Ultrasonography; Back-scattering; Internal echoes; Posterior echoes; Quantitative analysis; ImageJ; FEATURES;

D O I：

10.1016/j.ultrasmedbio.2013.02.014

中图分类号：

O42 [声学];

学科分类号：

070206 [声学];

摘要：

The aims of this study were to elucidate sonographic and histologic features of pure mucinous carcinoma (P-MC) of the breast using quantitative analysis and to evaluate the relationship between quantitative analysis and visual qualitative assessment. Eleven P-MCs (nine patients) were evaluated qualitatively and quantitatively. Three experts assessed these sonographic images using the Breast Imaging Reporting and Data System (BI-RADS) lexicon. For assessment of internal echoes and posterior echoes, quantitative measures were determined using ImageJ software. Histologic thin sections were stained for classification into separate parts of the tumor (stroma, mucin and cancer cells) and were digitized. Internal echoes were isoechoic in 7 of 11 (63.6%) tumors and hypoechoic in 4 of 11 (36.4%); all P-MCs were "enhanced'' in qualitative evaluation. As internal echoes increased, the proportion of stroma increased and that of mucin decreased. The high level of internal echoes is correlated with reflection and back-scattering, which are caused mainly by the interface between mucin and stroma. (E-mail: kaoku@koto.kpu-m.ac.jp) (c) 2013 World Federation for Ultrasound in Medicine & Biology.

引用

页码：1158 / 1167

页数：10

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