Four highly oxygenated isopimarane-type diterpenes of Orthosiphon stamineus

被引：43

作者：

Awale, S

Tezuka, Y

Banskota, AH

Kouda, K

Tun, KM

Kadota, S

机构：

[1] Toyama Med & Pharmaceut Univ, Dept Nat Prod Chem, Inst Nat Med, Toyama 9300194, Japan

[2] Minist Hlth, Yangon, Myanmar

来源：

PLANTA MEDICA | 2002年 / 68卷 / 03期

关键词：

D O I：

10.1055/s-2002-23137

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Four highly oxygenated isopimarane-type diterpenes, named orthosiphols O, P and Q and nororthosiphonolide A, have been isolated from the aerial parts of Orthosiphon stamineus from Myanmar, together with three known diterpenes, orthosiphols D and E and orthosiphonone A. Their structures were determined on the basis of extensive spectral analysis. All the isolated compounds displayed mild antiproliferative activities against highly liver metastatic colon 26-L5 carcinoma and human HT-1080 fibrosarcoma cell lines.

引用

页码：286 / 288

页数：3

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