CD1-mediated immune responses to glycolipids

被引：67

作者：

Burdin, N ^{[1
]}

Kronenberg, M ^{[1
]}

机构：

[1] La Jolla Inst Allergy & Immunol, Div Dev Immunol, San Diego, CA 92121 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0952-7915(99)80052-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Major advances have recently been accomplished in understanding the biochemistry of interactions between lipid antigens and CD1. The diversity of lipid antigens loaded onto CP1 molecules in normal cells, the ligand requirements for CD1 recognition by autoreactive T cells,including NK T cells, and the significance of CD1-mediated autoreactivity, as opposed to pathogen reactivity, remain controversial issues.

引用

页码：326 / 331

页数：6

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