NMR-guided fragment-based approach for the design of AAC(6′)-Ib ligands

被引:25
作者
Lombes, Thomas [2 ]
Begis, Guillaume [2 ]
Maurice, Frederique [1 ]
Turcaud, Serge [2 ]
Lecourt, Thomas [2 ]
Dardel, Frederic [1 ]
Micouin, Laurent [2 ]
机构
[1] Univ Paris 05, RMN Biol, CNRS, F-75006 Paris, France
[2] Univ Paris 05, UMR 8638, CNRS, F-75006 Paris, France
关键词
aminoglycosides; antibiotics; coenzyme A; fragment-based synthesis; NMR spectroscopy;
D O I
10.1002/cbic.200700677
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:1368 / 1371
页数:4
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