A non-invasive method for observing hippocampal function

被引：38

作者：

Hanlon, FM

Weisend, MP

Huang, MX

Lee, RR

Moses, SN

Paulson, KM

Thoma, RJ

Miller, GA

Cañive, JM

机构：

[1] New Mexico VA Hlth Care Syst, Albuquerque, NM 87108 USA

[2] Univ New Mexico, Dept Radiol, Albuquerque, NM 87131 USA

[3] Univ New Mexico, Dept Psychol, Albuquerque, NM 87131 USA

[4] Univ New Mexico, Dept Psychiat, Albuquerque, NM 87131 USA

[5] Univ Illinois, Dept Psychol, Urbana, IL 61801 USA

[6] Univ Illinois, Dept Psychiat, Urbana, IL 61801 USA

[7] Univ Illinois, Beckman Inst, Urbana, IL 61801 USA

来源：

NEUROREPORT | 2003年 / 14卷 / 15期

关键词：

configural; hippocampus; learning; MEG; memory; relational; stream; transverse patterning; visual;

D O I：

10.1097/00001756-200310270-00015

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A non-invasive method for observing the functioning of the hippocampus could be invaluable in understanding the role of hippocampal abnormalities in many brain disorders. Transverse patterning, a hippocampal-dependent memory task, was used in an attempt to study the functioning hippocampus. Subjects performed transverse patterning while whole-head MEG data were collected. The MEG data were analyzed using a spatial-temporal multiple-dipole approach. Controls showed right hippocampal activation. Patients with unilateral hippocampal damage showed activation in undamaged hippocampus. MEG during transverse patterning performance is a promising, non-invasive tool for assessing hippocampal function.

引用

页码：1957 / 1960

页数：4

共 25 条

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