Gold-coated iron nanoparticles:: a novel magnetic resonance agent for T1 and T2 weighted imaging

被引：111

作者：

Cho, SJ

Jarrett, BR

Louie, AY ^{[1
]}

Kauzlarich, SM

机构：

[1] Univ Calif Davis, Dept Biomed Engn, Davis, CA 95616 USA

[2] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA

来源：

NANOTECHNOLOGY | 2006年 / 17卷 / 03期

关键词：

D O I：

10.1088/0957-4484/17/3/004

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Core/shell structured iron(Fe)/gold(Au) nanoparticles have been prepared by a reverse micelle method, and their potential application as magnetic resonance (MR) contrast agent investigated. The average nanoparticle size is 19 rim, as determined by x-ray powder diffraction (XRD) and transmission electron microscopy (TEM). Magnetic properties and relaxivities of nanoparticles are presented and compared. The saturation magnetization Is 81 emu g(-1) Fe for freshly prepared nanoparticles and the particles have high r(1) (6.87 mM(-1) s(-1)) when the Fe core is kept from oxidation. These nanoparticles may be used as T-1 agents in the unoxidized form.

引用

页码：640 / 644

页数：5

共 46 条

[1] Comparative study of ferrofluids based on dextran-coated iron oxide and metal nanoparticles for contrast agents in magnetic resonance imaging [J].