Follow-up of Children Born after ART

被引：74

作者：

Basatemur, E. ^{[1
]}

Sutcliffe, A. ^{[1
]}

机构：

[1] UCL, Adolescent & Gen Paediat Unit, Inst Child Hlth, London NW1 2PQ, England

来源：

PLACENTA | 2008年 / 29卷

关键词：

Follow-up; Assisted reproductive therapies; ART; In vitro fertilisation; IVF; Intracytoplasmic sperm injection; ICSI;

D O I：

10.1016/j.placenta.2008.08.013

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

Assisted reproductive therapies (ART), namely in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI), have become widely used in the treatment of human infertility. Children conceived using ART represent a substantial proportion of the population. Follow-up of these children is necessary in order to evaluate the risks of infertility treatment upon subsequently conceived offspring. In recent years there has been considerable work in this field. This review summarises current evidence regarding the health of children conceived following ART, encompassing neonatal outcomes, the risk of congenital malformations, neurodevelopmental outcome, physical health, psychosocial well being, and the risk of cancer. The main risks for the future well being of ART children remain multiple pregnancies and low birth weight. Evidence regarding the outcome of singletons born at term following ART is generally reassuring. It is essential that follow-up of ART children continues as they progress through adolescence into adulthood. (C) 2008 Elsevier Ltd. All rights reserved

引用

页码：S135 / S140

页数：6

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