Throwing the switch in bacterial chemotaxis

被引：47

作者：

Silversmith, RE ^{[1
]}

Bourret, RB ^{[1
]}

机构：

[1] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27599 USA

来源：

TRENDS IN MICROBIOLOGY | 1999年 / 7卷 / 01期

关键词：

D O I：

10.1016/S0966-842X(98)01409-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In Escherichia coli chemotaxis, the switch from counterclockwise to clockwise rotation of the flagella occurs as a result of binding of the phosphorylated CheY protein to the base of the flagellum. Analysis of CheY variants has provided a picture of the surface of CheY that undergoes conformational shifts, as a result of phosphorylation, to interact directly with the flagellum.. Whether phospho-CheY binding and flagellar switching are sequential steps or can occur in a concerted fashion has yet to be determined.

引用

页码：16 / 22

页数：7

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