Effect of Thapsia essential oils on bile composition in rats

被引:3
作者
Avato, P
De Ruvo, C
Cellamare, S
Carotti, A
Mazzoccoli, M
Siro-Brigiani, G
机构
[1] Univ Bari, Dipartimento Farmacochim, I-70125 Bari, Italy
[2] Univ Bari, Ist Farmacol, I-70124 Bari, Italy
关键词
bile acids; choleretic activity; plant essences; Thapsia;
D O I
10.1076/phbi.36.5.335.4652
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The effect on rat bile composition of the essential oils from the fruits of three different chemotypes of Thapsia has been studied. For comparison, the major components of Thapsia essential oils, limonene, geranylacetate and methyleugenol, as well as menthol and peppermint oil, were also included in the investigation. Data obtained show that the tested drugs enhance bile secretion by increasing bile acid-independent flow (BAIF). Biotransformation products of the tested drugs were detected in bile samples.
引用
收藏
页码:335 / 340
页数:6
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