Doing randomized controlled trials in a developing country: Some practical realities

被引:2
作者
Glasgow, NJ
Murdoch, JC
Baynouna, L
AlSabosy, MMA
AlJabiri, ONK
Harron, DWG
机构
[1] Department of Family Medicine, FMHS, University of the United Arab Emirates, Al-Ain
关键词
developing countries; drug treatment; hypertension; randomized controlled trials; United Arab Emirates;
D O I
10.1093/fampra/13.1.98
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background. Formal randomized controlled trial results are often reported. The difficulties of doing such trials are not. Developing countries represent a new field in which trials can be undertaken. In this context even less is known about the practicalities involved. Method and results. A randomized, double-blind, parallel study took significantly longer than expected to complete and subject recruitment and participation fell short of expectations. Different recruitment strategies were used and these performed differently in terms of enrolling trialists. Subjects most frequently left the trial in its early stages. Conclusions. Possible explanations for these findings include the demography of the country, cultural factors, and the existence of an established doctor-patient relationship.
引用
收藏
页码:98 / 103
页数:6
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