A convenient and effective method for synthesizing β-amino-α,β-unsaturated esters and ketones

被引：82

作者：

Gao, YH ^{[1
]}

Zhang, QH ^{[1
]}

Xu, JX ^{[1
]}

机构：

[1] Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, Minist Educ,Key Lab Bioorgan Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2004年 / 34卷 / 05期

基金：

中国国家自然科学基金;

关键词：

amination; beta-diketone; beta-keto ester; beta-amino-alpha; beta-unsaturated ketone; beta-unsaturated ester; silica gel;

D O I：

10.1081/SCC-120028364

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and effective method for the preparation of beta-amino-alpha,beta-unsaturated esters and ketones has been developed through silica gel-catalyzed and solvent-free reactions of beta-dicarbonylic compounds with ammonia and primary amines.

引用

页码：909 / 916

页数：8

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