Microbiology and Antimicrobial Susceptibility Patterns of Commensal Flora in the Middle Nasal Meatus

被引:12
作者
Kirtsreesakul, Virat [2 ]
Tuntaraworasin, Jompon [2 ]
Thamjarungwong, Benjamas [1 ]
机构
[1] Prince Songkla Univ, Fac Med, Div Microbiol, Dept Pathol, Hat Yai, Thailand
[2] Prince Songkla Univ, Fac Med, Dept Otolaryngol, Div Allergy & Rhinol, Hat Yai, Thailand
关键词
antimicrobial susceptibility; bacteriology; commensal flora; middle nasal meatus; nasal endoscopy;
D O I
10.1177/000348940811701209
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objectives: We examined the microbiology and antimicrobial susceptibility patterns of commensal flora in the middle nasal meatus of normal subjects who were free of health care-associated risks and sinonasal disease. Methods: A prospective study was performed on 70 healthy volunteers without health care-associated risks or sinonasal disease. Middle meatal specimens were carefully taken by an endoscopically guided swab technique. The specimens were cultured for aerobic and anaerobic bacteria. Antimicrobial susceptibility testing was performed by the broth disc method. Results: Bacterial growths were recovered in 66 of the 70 specimens (94.3%). Coagulase-negative staphylococci (CNS) were the most common isolates (61.6%), followed by Staphylococcus aureus (11.6%) and Corynebacterium sp (9.3%). All growths were quantified as very rare (73.3%), rare (13.9%), or few (12.8%). Obligate anaerobic bacteria were not identified. The samples positive for CNS showed multiple resistances to antibiotics, including erythromycin stearate (30.2%), clindamycin hydrochloride (28.3%), oxacillin sodium (a clinical substitute for methicillin sodium; 18.9%), and sulfamethoxazole-trimethoprim (9.4%). Conclusions: A small amount of CNS with or without multiple antibiotic resistances and/or S aureus cultured from the middle meatus can be considered contaminants in middle meatal culture during an episode of rhinosinusitis.
引用
收藏
页码:914 / 918
页数:5
相关论文
共 29 条
[1]  
ALMADORI G, 1986, Rhinology (Utrecht), V24, P257
[2]   Endoscopically directed middle meatal cultures versus maxillary sinus taps in acute bacterial maxillary rhinosinusitis: A meta-analysis [J].
Benninger, MS ;
Payne, SC ;
Ferguson, BJ ;
Hadley, JA ;
Ahmad, N .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2006, 134 (01) :3-9
[3]   Bacterial infection in chronic rhinosinusitis: A controlled paired analysis [J].
Bhattacharyya, N .
AMERICAN JOURNAL OF RHINOLOGY, 2005, 19 (06) :544-548
[4]  
Biel MA, 1998, ANN OTO RHINOL LARYN, V107, P942
[5]   Microbiology of chronic maxillary sinusitis: Comparison between specimens obtained by sinus endoscopy and by surgical drainage [J].
Brook, I ;
Frazier, EH ;
Foote, PA .
JOURNAL OF MEDICAL MICROBIOLOGY, 1997, 46 (05) :430-432
[6]   Microbiology of chronic ethmoid sinusitis: Is this a bacterial disease? [J].
Busaba, NY ;
Siegel, NS ;
Salman, SD .
AMERICAN JOURNAL OF OTOLARYNGOLOGY, 2004, 25 (06) :379-384
[7]   Comparison of antral tap with endoscopically directed nasal culture [J].
Casiano, RR ;
Cohn, S ;
Villasuso, E ;
Brown, M ;
Memari, F ;
Barquist, E ;
Namias, N .
LARYNGOSCOPE, 2001, 111 (08) :1333-1337
[8]  
Chan J, 2001, Ear Nose Throat J, V80, P143
[9]   Concordance of middle meatal swab and maxillary sinus aspirate in acute and chronic sinusitis: A meta-analysis [J].
Dubin, MG ;
Ebert, CS ;
Coffey, CS ;
Melroy, CT ;
Sonnenburg, RE ;
Senior, BA .
AMERICAN JOURNAL OF RHINOLOGY, 2005, 19 (05) :462-470
[10]   Role of middle meatus aspiration culture in the diagnosis of chronic sinusitis [J].
Gold, SM ;
Tami, TA .
LARYNGOSCOPE, 1997, 107 (12) :1586-1589